review-biomarker-fit-purposelisted

# Review Biomarker Fit Purpose Biomarker fit-for-purpose evidence pack — bounded review / prepare / structure workflow for the L3 task **Biomarker fit-for-purpose** (Band A · Scientific foundations). **Skills review, reconcile, verify, structure and flag. **Qualified humans decide, approve, sign off, submit and act.**** ## Four-box contract | Box | Content | |---|---| | **Trigger** | Please review the materials for Biomarker fit-for-purpose and produce a sourced finding register — do not decide the clinical or regulatory outcome. | | **Input** | Primary package for Biomarker fit-for-purpose plus the supporting pack in Required inputs | | **Output** | Source-linked finding register with denominators; gap / contradiction flags; refuse list | | **Refuses** | Decide the outcome of Biomarker fit-for-purpose; approve or submit related documents; select or adjust a dose; speak for the sponsor to an agency | ## Who this is for Clinical pharmacology or pharmacometrics practitioners working on **Scientific foundations** who need a repeatable, sourced pass over **Biomarker fit-for-purpose** — not a decision and not a filing. ## When to use this skill - "Please review the materials for Biomarker fit-for-purpose and produce a sourced finding register — do not decide the clinical or regulatory outcome." - "What is evidenced, missing, or inconsistent for: Biomarker fit-for-purpose?" - "Trace every material statement about Biomarker fit-for-purpose to a locator." - "Prepare the revie