review-adme-routes-eliminationlisted

# Review Adme Routes Elimination ADME and routes of elimination evidence pack — bounded review / prepare / structure workflow for the L3 task **ADME and routes of elimination** (Band A · Scientific foundations). **Skills review, reconcile, verify, structure and flag. **Qualified humans decide, approve, sign off, submit and act.**** ## Four-box contract | Box | Content | |---|---| | **Trigger** | Please review the materials for ADME and routes of elimination and produce a sourced finding register — do not decide the clinical or regulatory outcome. | | **Input** | Primary package for ADME and routes of elimination plus the supporting pack in Required inputs | | **Output** | Source-linked finding register with denominators; gap / contradiction flags; refuse list | | **Refuses** | Decide the outcome of ADME and routes of elimination; approve or submit related documents; select or adjust a dose; speak for the sponsor to an agency | ## Who this is for Clinical pharmacology or pharmacometrics practitioners working on **Scientific foundations** who need a repeatable, sourced pass over **ADME and routes of elimination** — not a decision and not a filing. ## When to use this skill - "Please review the materials for ADME and routes of elimination and produce a sourced finding register — do not decide the clinical or regulatory outcome." - "What is evidenced, missing, or inconsistent for: ADME and routes of elimination?" - "Trace every material statement about ADME and routes of