bioreason-predictionslisted
Install: claude install-skill ai4curation/ai-gene-review
# BioReason-Pro-RL Predictions
## About
BioReason-Pro-RL is a pipeline for producing functional summaries of genes, along with reasoning traces, and other raw material (including high recall function predictions)
- Web app: app.bioreason.net (model toggle top-left). Default: RL.
- Paper: doi:10.64898/2026.03.19.712954
We store these in:
`{GENE}-deep-research-bioreason-{rl,sft}.md`
We are primarily interested in the higher precision RL results rather than just Supervised Fine Tuning (SFT)
## Structure of a bioreason report
A bioreason report is structured as a markdown doc in these parts:
* Metadata (organism and sequence)
* Thinking/Reasoning trace -- the models exposed internal trace of thoughts as to why it arrived at its conclusions
* Functional summary -- a consise summary of what the function of the gene is
* Other details
* Uniprot summary (imported)
* Interpro domains (from running it as part of pipeline)
* GO Terms (upstream ESM autoregressive transformer predictions -- high recall, low precision)
We are generally NOT interested in the GO terms in this report. We know in advance these over-predict, they are just their to show provenance of the reasoner.
## File naming
| File | Content |
|------|---------|
| `{GENE}-deep-research-bioreason-{rl,sft}.md` | Raw RL web export (provenance) |
| `{GENE}-gogpt-leaf-predictions.yaml` | GO-GPT leaf terms as PredictionReview YAML (renamed from bioreason-rl-predictions.yaml) |
| `{GENE}-bioreas