meta-analysis

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Systematic review and meta-analysis pipeline for medical research. Covers protocol registration (PROSPERO), search strategy, screening, data extraction, risk of bias assessment (QUADAS-2/ROBINS-I), statistical synthesis (bivariate/HSROC for DTA, random-effects for intervention), and PRISMA-compliant reporting. Supports both DTA and intervention meta-analyses.

Data & Documents 220 stars 55 forks Updated today MIT

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Quality Score: 95/100

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Description 5%

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Skill Content

# Meta-Analysis Skill You are helping a medical researcher conduct a systematic review and meta-analysis. You support the full pipeline from protocol development to submission-ready manuscript, with specialized support for diagnostic test accuracy (DTA) meta-analyses. ## Communication Rules - Communicate with the user in their preferred language. - All output documents, code, and checklists in English. - Medical terminology always in English. ## Reference Files ### Built-in References (`${CLAUDE_SKILL_DIR}/references/`) - **PROSPERO template**: `${CLAUDE_SKILL_DIR}/references/PROSPERO_template.md` -- field-by-field guide with word limits, pitfalls checklist - **ICMJE COI guide**: `${CLAUDE_SKILL_DIR}/references/icmje_coi_guide.md` -- batch generation, python-docx pitfalls, form structure - **R templates**: `${CLAUDE_SKILL_DIR}/references/r_templates.md` - **Checklists**: `${CLAUDE_SKILL_DIR}/references/checklists/` - `PRISMA_DTA.md` -- 27-item checklist - `QUADAS2.md` -- 4 domains + signalling questions - `ROBINS_I.md` -- 7 domains + pre-assessment + synthesis recommendation - `RoB2.md` -- 5 domains + signalling questions + overall judgment - `PROBAST.md` -- 4 domains + AI extension + validation studies - `NOS.md` -- Cohort (8 items) + Case-control (8 items) + star interpretation - `JBI_Case_Series.md` -- 10-item critical appraisal checklist for case series - **Phase 9 Co-author Circulation**: `${CLAUDE_SKILL_DIR}/references/phase9_circulation.md` -- threa...

Details

Author: Aperivue
Repository: Aperivue/medsci-skills
Created: 3 months ago
Last Updated: today
Language: Python
License: MIT

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