alterlab-lamindb

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Manage, annotate, and trace biological data with LaminDB, an open-source FAIR data framework that makes datasets queryable, versioned, and reproducible. Use when registering or querying biological datasets (scRNA-seq, spatial, flow cytometry), validating and curating data against ontologies (genes, cell types, diseases, tissues), tracking data lineage and computational workflows, building data lakehouses, or wiring integrations with Nextflow, Snakemake, W&B, or MLflow. Part of the AlterLab Academic Skills suite.

AI & Automation 66 stars 13 forks Updated 1 weeks ago MIT

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Skill Content

# LaminDB ## Overview LaminDB is an open-source data framework for biology designed to make data queryable, traceable, reproducible, and FAIR (Findable, Accessible, Interoperable, Reusable). It provides a unified platform that combines lakehouse architecture, lineage tracking, feature stores, biological ontologies, LIMS (Laboratory Information Management System), and ELN (Electronic Lab Notebook) capabilities through a single Python API. **Core Value Proposition:** - **Queryability**: Search and filter datasets by metadata, features, and ontology terms - **Traceability**: Automatic lineage tracking from raw data through analysis to results - **Reproducibility**: Version control for data, code, and environment - **FAIR Compliance**: Standardized annotations using biological ontologies ## When to Use This Skill Use this skill when: - **Managing biological datasets**: scRNA-seq, bulk RNA-seq, spatial transcriptomics, flow cytometry, multi-modal data, EHR data - **Tracking computational workflows**: Notebooks, scripts, pipeline execution (Nextflow, Snakemake, Redun) - **Curating and validating data**: Schema validation, standardization, ontology-based annotation - **Working with biological ontologies**: Genes, proteins, cell types, tissues, diseases, pathways (via Bionty) - **Building data lakehouses**: Unified query interface across multiple datasets - **Ensuring reproducibility**: Automatic versioning, lineage tracking, environment capture - **Integrating ML pipelines**: ...

Details

Author
AlterLab-IEU
Repository
AlterLab-IEU/AlterLab-Academic-Skills
Created
5 months ago
Last Updated
1 weeks ago
Language
Python
License
MIT

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